Archive for the ‘Aging skin’ Category

Is Tanning An Addiction?

August 24, 2011

Yes, according to the findings recently published in the Journal of Addiction Biology.  People who regularly use tanning beds experience changes in brain activity that mimic patterns of drug addiction.  The study’s author, Dr. Byron Adinoff, a psychiatry professor at the University of Texas Southwestern Medical Center, explains that several parts of the brain that play a role in addiction were activated when the subjects were exposed to UV rays.

“What this shows is that the brain is in fact responding to UV light and it responds in areas that are associated with reward.  These are areas, particularly the striatum, that we see activated when someone is administered a drug or high-value food like sugar”, Dr. Adinoff states.  He continues to state that the research suggests that some people appear addicted to tanning, a finding bolstered by the fact that many long-term tanners have a difficult time stopping or even cutting back on their sessions under the tanning bed.

My thoughts:  self-tanning lotions are not addictive, are safe and look attractive, if tan is a look you’re going for.

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Is There An Association Between Wrinkles And Bone Density?

July 17, 2011

A recent study presented at the annual meeting of The Endocrine Society explored the association between bone mineral density and skin wrinkling.  Dr. Lubna Pal, a reproductive endocrinologist and professor at Yale School of Medicine, scored 144 postmenopausal women’s face and neck wrinkles (based on the number of sites and depth).  Bone mineral density was measured with DEXA, or dual-energy x-ray absorptiometry.

Dr. Pal and her associates found a significant association between wrinkle severity and bone density  More severe wrinkling was associated with lower bone density.  “In postmenopausal women, the appearance of the skin may offer a glimpse at the skeletal well-being, a relationship not previously described.  This information may allow the possibility of identifying postmenopausal women at fracture risk at a glance without dependence on costly tests”.

One common denominator between skin and bone is collagen.  Changes in collagen with age may affect both areas.

Periocular Wrinkling

January 11, 2011

If you are concerned about wrinkles around your eyes, then consider the recently-conducted clinical study by Episciences, Inc.  In a blinded, controlled clinical trial, two dual-action cosmeceutical products (Epionce Lite Lytic and Lytic Lotions) produced a statistically significant visible reduction in periocular wrinkles of 48.3% over a period of 8 weeks.  The Epionce products consist of blends of unique botanical extracts that have keratolytic (exfoliating) effects and prevent the release and activation of proinflammatory factors (leading to wrinkles).

Without the addition of soy, alpha hydroxy acids, retinoids, teas, vitamins or traditional antioxidants….ingredients found in many anti-aging products…both the Lite Lytic and Lytic Lotions are a new addition to the anti-aging armamentarium.  Formulated with non-irritating botanicals, these two products are suitable for even the most sensitive skin.

Ccontact Peels To The People for more information or samples of these and other fine Epionce products.

 

Ergothioneine: Mushroom Magic for Skin

November 7, 2010

Ergothioneine protects the skin from oxidative and DNA damage.   It is an antioxidant, protecting the mitochondrial membrane against oxidation.   It will transfer fatty acids into the mitochondria to help use oxygen efficiently and to produce more energy.  It also protects DNA from the oxidation of guanine.  Ergothioneine reduces TNF-Alpha (Tumor Necrosis Factor), a stress signal cytokine.

It is also one of five primary anti-aging ingredients found in Peels To The People’s Cell Youth Actif.  After a decade of research and multiple patents, CYA is now available from PTTP.  This exciting gel-like serum in an pump container fully compliments my other Peels products intended to correct cellular damage:  Vitamin C Intensive Serum and Retinol Resurfacing Complex.

Sun Protection Trends

May 18, 2010

There are two growing trends in sun protection formulations.  The first is to include multifunction ingredients that offer additional benefits  to the client, such as antioxidants and anti-aging botanicals.    The second is to improve the aesthetics of the product, making it pleasant enough that the client will use it on a daily basis.

New formulations are lighter weight and more easily absorbed.  Case in point:  Epionce’s Active Shield SPF 30 and Ultimate Shield SPF 50 include higher percentages of cosmetically-elegant zinc oxide (9.2% and 10.1% respectively) as well as antioxidants and botanical acids and extracts.  Both are most appropriate for normal to dry skin types and are rapidly absorbed.

Electric Stimulation

April 28, 2010

Today I quote and/or paraphrase from a recent article by Leslie Baumann, M.D. in Skin & Allergy News, March 2010, p. 23 entitled “Electric Stimulation”.    After a brief discussion of the benefits of increasing collagen and elastin to decrease the effects of aging, Dr. Baumann eventually gets around to electric stimulation to stimulate wound healing (aka aging skin).

“I am intrigued with the idea of an electromimetic current being used to stimulate fibroblasts.  The notion of harnessing the natural electric currents of skin cells to increase collagen and elastin production is fascinating for several reasons, not the least of which is elimination of the issue of penetration of active ingredients.  A charge generated on the cells in the top layer will likely propagate to neighboring cells.  An enhancement of cell-to-cell communication would seem likely to extend to the lower layers, allowing the cells deeper in the dermins to ‘get the message'”.

She’s talking about microcurrent, as well as ingredients such as zinc and copper that harness electrical currents to stimulate fibroblasts into synthesizing collagen and elastin.   For those of us who see the results of microcurrent stimulation for anti-aging, this is old news.  And yet it’s gratifying that a dermatologist gets it and is curious.

Esoteric Information

March 8, 2010

I enjoy reading about new “age-defying” ingredients.  One of the best sources I’ve found is this website:   www.cosmeticsandtoilteries.com.  You can find the latest patents, product releases, skin care controversies, and just about anything you want about the world of cosmetics, skin care products, bath care products, and so forth. 

Check it out!

Next Generation of AHAs

February 15, 2010

New to the Peels To The People anti-aging arsenal comes Age-Limit, a new generation of alphahydroxy acids (AHAs).  In the 1990s, AHAs were the most remarkable skin treatments ever developed for aging or problem skin.  But they had one big drawback:  irritation.

Age-Limit solves this problem with the AHAminoPlex molecule – a complex of glycolic acid and a naturally derived amino acid to ensure maximum acid delivery without penetrating skin’s zone of irritation.  This patented technology, developed by Drs. Yu and Van Scott, the pioneers of AHA skin therapy, is the next generation of AHAs.

This safe and effective new product is available now!  Coupled with periodic chemical peels, results are phenomenal.

Skin Science from Procter & Gamble

January 22, 2010
I came across this article on gene expression research from Procter & Gamble’s skin science website:  www.pgbeautygroomingscience.com.  P & G’s site has many excellent  and readable synopsis of research results on skin health and aging.  Below is verbatim from this site.  The photos of young vs. old skin are not available to view unless you go directly to P & G’s site.

Gene Expression Research Reveals Causes of Wrinkles, Age Spots

In the past, scientists studying aging skin have looked at various skin properties – thickness, color, moisture barrier, proteins, and internal cell structures. Today, P&G Beauty scientists are studying the differences between young and aged skin at the most fundamental level possible – gene expression. “The expression of your genetic code as it reacts to environmental change controls all the metabolic processes necessary for good skin health and function,” says P&G Beauty geneticist Dr. Jay Tiesman, PhD. “Now we understand which genes become either disabled or overactive as your skin gets older, resulting in the physiological changes we see as wrinkles and age spots.”

Young vs. Old, Protected vs. Exposed

Research analyzed skin samples collected from ten young and ten aged female subjects (18-20 and 60-67 years). Scientists collected skin biopsies of buttocks to test intrinsically aged skin and biopsies of forearms for extrinsically aged skin. The buttock and forearm biopsies were selected because of their relative exposure, or lack thereof, to environmental elements that may impact aging. Additionally, Affymetrix gene chip technology was used to examine the gene expression differences in the samples to reveal the underlying biological mechanisms responsible for the appearance of skin aging. The study allowed scientists to identify pathways that are active in young skin but inactive in old skin, as well as those that are overly active in older skin.

Young and old skin biopsies

Young and old skin biopsies

Sun Exposure Alters Skin Immune Function

One provocative finding was that aging associated with environmental factors, such as UV, not only accelerated the changes in natural aging genes as expected, but also turned on other gene responses. For example, the study demonstrates the magnitude of altered immune and inflammatory gene expression resulting from the photodamage process. This is important as recent scientific literature shows that UV-altered immune response in skin can increase susceptibility to skin cancer.

Driving Future Skin Anti-Aging Advances

This research is expected to drive breakthrough advances in both prevention and treatment of the signs of aging skin over the coming decades. By understanding how the expression of specific genes are modulated by the aging process, scientists now have the means to develop treatments to modify those processes that age skin considerably. “In the future, certain processes such as inflammation, proteolysis, lipid biosynthesis, or cellular differentiation, known to be involved in the breakdown of skin as it ages, may be able to be regulated,” speculates Dr. Michael Robinson, Principal Scientist, P&G Global Biotechnology, lead author on the study.

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